health care
Wellness: Health Care
Cognitive Dysfunction Syndrome:
Old Dog Senility

Cognitive Dysfunction Syndrome, also referred to as “old dog senility” or “sundowner syndrome” is a common syndrome that is categorized as a slow, degenerative and progressive disorder in our aging pets. This process leads to changes in awareness, a decreased responsiveness to normal surroundings, and potentially increased signs of anxiety that usually worsen in the night hours. 

There are many signs observed with cognitive changes and they can be lumped into some general symptoms as follows:

  • Disorientation: such as going to the wrong side of the door to be let outside or getting lost in familiar environments.
  • Altered interactions: there may be increased irritability, anxiety or agitation.
  • Alterations in sleep-wake cycles: this is most often observed as increased restlessness (especially at night) and/or vocalizations that are seemingly directed at nothing in particular; as the disease progresses, you may continue to notice worsening of these signs and begin to see your pet aimlessly wandering the house with compulsive behaviors such as barking at the wall for no apparent reason or excessive grooming.
  • Normal and previously learned behaviors may change: you may notice your dog becoming less adept at its normal tasks, such as house training or responding appropriately to previously learned commands; you may also notice that your pet has difficulty recognizing and reacting to its familiar family members.
  • The above changes generally begin very gradually, so much so, that many pet parents fail to recognize the early stages of the disease and often attribute their pets subtle alterations in behavior to “simply getting older.” A recent study at the University of California School of Veterinary Medicine demonstrated just how common these observations are: out of 69 dogs participating, 32% of the 11-year old dogs were affected by this syndrome and 100% of the dogs 16 years of age older were affected (source: Veterinary Information Network).

    The exact reason for this change in our geriatric pets is unknown, but it is thought that the body’s normal degenerative and age-related changes contribute to the dysfunction. These changes include central nervous system deterioration, oxidative stress, accumulation of free radicals, and cell death. Signs are unfortunately progressive and treatment is aimed at prevention and/or slowing the progression of disease for which lifelong therapy is required once diagnosed. 

    Treatment is the utilization of a multi-modal approach to managing signs, meaning, a combination of synergistic therapies that are based on the severity of the clinical signs.  Selegiline is a prescription medication that is used to help control more severe symptoms, and it is thought to improve transmission of brain chemicals (dopamine) as well as have protective effects on the brain’s nerve cells. 

    There has also been the development of commercial and prescription “senior diets” that have demonstrated improvements in cognitive function, such as Hill’s b/d ("brain diet").  Natural supplements have shown promise in managing signs and slowing the course of disease by reducing the neurological damage caused by free radicals.They include antioxidants (vitamins C and E, selenium, flavonoids), gingko bilboa, Omega-3 fatty acids, and medium chain triglycerides to name a few. Pheromone therapy and melatonin may ease anxiety and promote a feeling of well being for dogs that experience increased anxiety at night. And finally, environmental enrichment such as brisk brushing sessions, massage therapy, interactive toys, and stimulating walks is thought to be an important cornerstone in slowing the progression by stimulating brain activity. Maintaining a stimulating environment, and engaging in as much activity as is practical for your pet’s age and health, may help prevent or delay the onset of cognitive decline as your pet moves into its golden years.

    I will end with one of my favorite veterinary mantras, which is: “Old age is not a disease” (for which I am personally more thankful for each day), and with proper care, our senior “babies” can go on experiencing a good quality of life as cognitive changes develop. 





    Wellness: Health Care
    Spaying Alternatives
    A Kinder Cut? Advances in spay procedures
    Advances in spay procedures

    As a colleague of mine once said, “a spay is a procedure routinely performed, but it is not a routine procedure.” In the U.S., “spay” refers to the surgical removal of the ovaries and uterus. In Europe, however, removal of just the ovaries (ovariectomy) appears to be the most popular sterilization technique. Why are my European colleagues doing things differently, and is there evidence to suggest that they’re right? Is it possible to achieve the same surgical result using a less-complicated, less-involved procedure?

    It’s been proven that an ovariectomy, which can be done via laparoscopy (or “keyhole” surgery), requires a smaller incision. Still, to date, no one has proven that removing both the uterus and the ovaries is more painful than taking just the ovaries, and no one has compared complication rates between the two surgical techniques.

    However, other aspects have been assessed. In the Journal of the American Veterinary Medical Association, Michael DeTora, DVM, and Robert J. McCarthy, DVM, MS, DACVS, examined the two approaches.* Judging by their report, removing only the main hormone producers — the ovaries — has a lot going for it. Here are a few of their leading points.

    One of the big benefits to spaying is the decreased incidence of mammary gland tumors, the most common tumor in female dogs. Sterilize before the first heat and your dog is 200 times less likely to develop breast cancer when compared to a sexually intact dog. Taking or leaving the uterus will not change this risk; rather, the benefit comes from removing the ovaries and their sex hormones.

    It has been argued that there are two important reasons to remove the uterus. The first is the risk of developing pyometra, a uterine infection. Typically, pyometra occurs in dogs who have not been spayed and is attributed to the long-term influence of sex hormones, particularly progesterone, produced by the ovaries. In a study of 135 dogs, 66 had a regular spay and 69 had only the ovaries removed. There were no episodes of pyometra in either group up to 11 years after the surgery. In other words, leaving the uterus does not mean your dog will get a uterine infection. Remove the ovaries and you remove the source of progesterone, which means that pyometra cannot occur.

    The second concerns the risk of leaving a redundant organ behind, potentially exposing the dog to a future uterine tumor. This appears reasonable until you consider that uterine tumors are extremely rare. In one study, just 11 of nearly 35,000 female dogs had a tumor of the uterus, and only one of these was cancerous. Benign uterine tumors are slow growing, don’t spread to other organs and are easily cured with surgery. The chance of your dog succumbing to uterine cancer is a lot slimmer than your lifetime risk of being killed in a car crash.

    This leaves urinary incontinence, one of the most frustrating side effects of spaying. Reportedly, as many as one in five sterilized female dogs will have a tendency to dribble urine after surgery. Exactly why this happens is poorly understood, but the presence or absence of the uterus appears to make no difference.

    As a veterinarian, one of my most important roles is to help owners make informed health-care decisions for their companion animals. Evidence-based medicine suggests that there is no recognized disadvantage to taking just the ovaries and leaving the uterus behind. Though inertia is always the biggest barrier to change, I may have a chance to influence the choice when asked the time-honored question, “What would you do if this were your dog?”

    “Easy. Take the ovaries. Leave the uterus.”

    Wellness: Healthy Living
    Making Pet Meds More Affordable
    Greater choice made available to pet owners
    More Affordable Pet Meds

    As politicians and voters squared off this fall, a little bill sat in committee on Capitol Hill, awaiting action that in all likelihood won’t happen. If it expires, it will probably be reintroduced at the next Congressional go-around in 2013. But even if it dies on the vine, the bill has opened debate on an issue that affects virtually every pet owner — the cost and availability of veterinary medications — and promises to keep the discussion going for years to come.

    If passed, the legislation (officially known as HR 1406: Fairness to Pet Owners Act of 2011-IH) will require vets to give clients a written copy of all prescriptions. It also will require them to notify clients, in writing, of the client’s option to have the prescription filled elsewhere, and to confirm (via fax or other means) any prescriptions sent to outside pharmacies. This is not a novel concept; a majority of veterinarians already do this for those who request it. The act would, however, make it mandatory for vets to provide the prescriptions without being asked.

    The bill is modeled on the Fairness to Contact Lens Consumers Act of 2003, which required eye doctors to give their patients a copy of their prescriptions, thus breaking the medical monopoly on those lucrative little bits of polymer. This “prescription portability” was credited with changing the entire contact-lens market, giving consumers freedom to comparison shop (making prices more competitive) and also improving the quality and safety of the products themselves by streamlining the supply chain and distribution system. In the world of veterinary medicine, prescription portability would, at least in theory, reassure bargainhunting consumers that they’re shopping around in a truly open (and safe) marketplace.

    HR 1406 was introduced April 2011 under the sponsorship of Representatives Jim Matheson (D-UT) and Lee Terry (R-NE) and was immediately sent to the Health subcommittee of the House Committee on Energy and Commerce, which must approve the bill before it can be voted upon by Congress. But because 2012 is an election year — one that most certainly hasn’t been dominated by debates over pet prescriptions — few observers predict any action. The legislative monitoring service GovTrack gives the bill a 1 percent chance of passing before the end of the 2012 session; not great odds, obviously, but not particularly bad, either, given that only about 4 percent of the bills introduced in 2009–2010 were enacted.

    “Most often, bills like this take five to seven years to get passed,” says Andrew Binovi, federal legislative manager of government relations for the ASPCA, which is supporting the bill. Alyson Heyrend, communications director for Rep. Jim Matheson, adds, “There is no action expected on the bill before the end of the session — it’s an election year. But we’ll most likely be reintroducing the bill next time. It’s a good bill, good for pet owners, good for consumers. In this economy, every little bit helps, and lots of people aren’t even aware that they have options when it comes to pet medications.”

    A Pocketbook Issue
    The subject of pet medications has been getting attention in other parts of the government as well. The Federal Trade Commission held a public workshop on the topic in October, and is expected to issue a report on its findings sometime in 2013. In its official statement, the FTC calls the price of pet meds “an important pocketbook issue for many consumers,” noting that the 62 percent of American households with pets spend roughly $7 billion annually for prescription and over-the-counter drugs for their companion animals.

    Like everything else in Washington, the Pet Owners Act has both fans and foes. According to the Center for Responsive Politics, eight organizations are registered to lobby on HR 1406, including Walmart and the National Association of Chain Drug Stores. “This bill allows consumers a choice when it comes to prescription medications for their pets, and Walmart supports efforts that give our customers a say where they purchase medicines and enable them to save money,” says Molly Philhours, a media relations rep. This support is hardly surprising, as the act would be a boon for Walmart and other big retailers, drug and grocery stores, says David Sprinkle, research director for Packaged Facts, a market research firm. “What we’re seeing is a natural progression, as the pet-health market moves toward greater parallelism with human healthcare.”

    However, the number of pets covered by health insurance is miniscule, arguably making the out-of-pocket cost of a pet’s prescription drugs an even bigger concern for consumers than their own meds. “Less than 1 percent of the cats and dogs in America are insured, so this is a huge issue for owners,” says Laura Bennett, CEO of Embrace Pet Insurance. “Even if this bill doesn’t go through, it’s already had a big impact.”

    Bones of Contention
    The bill’s biggest opponent is the American Veterinary Medicine Association, which has registered to lobby on it and is urging its members to voice their opposition. “We’re not opposed to our clients having their pets’ prescriptions, or filling them at accredited pharmacies, but we’re against the legislation because it’s redundant,” explains Ashley S. Morgan, DVM, AVMA’s assistant director of governmental relations. “We don’t need a federal law to mandate something that most vets have been doing on their own for some time.” She notes that 26 states already have laws that require essentially the same thing as the new bill stipulates, and that most consumers are well aware of the wide availability of pet prescription fulfillment options.

    The proposed legislation has another downside for vets: loss of revenue. While the impact will vary among individual practices, Morgan says, most veterinarians today make between 14 and 28 percent of their income from in-house drug sales. In addition, vets typically charge fairly high mark-ups, an average of 129 percent over wholesale, according to the American Animal Hospital Association. Many also charge a “dispensing fee,” typically an average of $9 per script. Morgan adds that the proposed law would drown vets in paperwork, and require clinic staff to spend an inordinate amount of time communicating with outside pharmacies. Most veterinarians will be forced to pass those extra expenses on to their clients.

    Until fairly recently, veterinarians were the sole source for prescription pet medications. But with the advent of online pet pharmacies, such as Drs. Foster and Smith (which began selling medications and other pet care products through its catalog in 1983 and online in 1998), price-conscious owners started taking their drug business elsewhere. And in 1994, with the passage of the Animal Medicinal Drug Use Clarification Act (AMDUCA), veterinarians could prescribe certain approved human drugs for animals. In many cases, this gave veterinary clients an option to choose between the animal and the human drug, and to buy those drugs from outside pharmacies.

    But this just means that vets are behind the times when it comes to setting their prices, says Bennett. She notes that many veterinarians deliberately undercharge for some services to keep clients happy; like restaurateurs who exponentially mark up the wine they sell to make up for value-priced entrees, these vets count on the sale of medications to make the balance sheet work. “If you’ve been relying on drug sales all this time, this is a wake-up call,” she says.

    Competition — and Choices
    According to Bruce Rosenbloom, chief financial officer of PetMed Express Inc., parent company of the online retailer 1800-PetMeds, pet owners today spend about $3.8 billion annually on prescription drugs for their companion animals, and vets make about 67 percent of those sales. (Packaged Facts’ estimate of vets’ share of drug sales is roughly the same.) PetMed Express’s research shows that big retailers like Target, Walmart and Walgreens sell about 22 percent of pet medications through their retail and online stores, while web and mailorder retailers like 1800-PetMeds and Amazon account for the remaining 11 percent.

    All of these outlets offer incentives to pet owners. Kroger, for example, sells a long list of generic pet drugs, including some of the most-prescribed for dogs — pain-relievers like tramadol and meloxicam and antibiotics like amoxicillin and cephalexin — at $4 per 30-day supply. Target’s PetRx program, available in more than 1,200 of its instore pharmacies, can fill veterinary prescriptions for animal-specific medications, and all Target pharmacies will fill pet scripts for human drugs (they offer many $4 generics, as well). At Walgreens, you can add your dog to your $35-a-year family membership in the discount pharmacy program. With that, you get reduced prices on pet prescriptions and access to over 400 generic medications priced at $12 for a 90-day supply. Stop ‘n Shop and Winn-Dixie stores fill human-equivalent scripts, and have arrangements with online pet pharmacies to get your dog’s meds to you in one to two days.

    For those who’d rather shop online, there are currently 18 web-based pet pharmacies accredited with the National Association of Boards of Pharmacy through its Veterinary-Verified Internet Pharmacy Practice Sites (Vet-VIPPS) program, each of which has its own offers and incentives. (There are also countless websites that aren’t accredited — or properly licensed — which the Food and Drug Administration and other groups strongly suggest you avoid.)

    All this competition is good news for consumers, says ASPCA’s Binovi, because it guarantees that pet owners will be able to fill prescriptions as cheaply as possible. “There are big benefits here for both pets and their guardians,” he says. “It’s not that the veterinarians were a problem, just that this bill would harmonize all the different state laws to guarantee that everyone has better access to these medications.”

    Keeping the cost of pet ownership down is especially important in this economy, he adds. “We know that economics weighs into the decision to adopt an animal and even, in some cases, to surrender an animal to a shelter.” There are no statistics on the number of owners citing the high cost of prescription drugs — or any other expense associated with keeping a pet — as the reason for surrender, but it’s not a great leap to suggest that someone who’s facing serious financial problems might see the family dog as an expense that could be eliminated. And even for an owner who’s not in dire straights, every little bit helps. “It’s always good to have more choices and better access, no matter what you’re buying,” he says.

    You can verify an online vendor’s Vet-VIPPS standing on the NABP website: nabp.net.

    Wellness: Health Care
    Bone Regeneration: From Science Fiction to Fact
    Bionic Dog
    Whisky - Bionic Dog

    Something was wrong with Whiskey, and it wasn’t lethargy, whining or refusal to eat that tipped off his owners. It was chew sticks, unchewed. For the 10-year-old Small Munsterlander, chewing was a lifelong obsession. It had been a good life, one spent running down San Francisco city sidewalks; playing in the parks; exploring neighborhood shops; and, of course, chasing toys on the beach.

    Whiskey’s owners, Tom Swierk and Robin Addams, indulged his appetite for beef tendons and other treats. The dog they had acquired as a young pup still had “lots of sass,” as Swierk describes him, or he did until last Thanksgiving, when his owners realized he had lost interest in chewing, one of his favorite pastimes. The Small Munsterlander, a hunting breed that originated in Munster, Germany, has been bred for centuries to thrive on chasing and retrieving. True to his roots, Whiskey was a friendly, devoted dog with an intense streak that his owners channeled into play. When Whisky ignored his chew toys, Swierk thought it was a problem with a tooth, and took him to the vet.

    It was cancer.

    Oral cancer, both malignant and benign, is not uncommon in dogs. Unfortunately, Whiskey’s tumor wasn’t benign. The lesion on his lower left gum was malignant squamous cell carcinoma, the second most common oral malignancy in dogs. In humans, it accounts for 70 percent of all oral tumors.

    The wrenching news came with a silver lining: the cancer hadn’t spread to other organs. “This type of malignant tumor metastasizes less than 10 percent of the time,” Swierk says. It is known for its aggressive growth, however, and the tumor had already invaded Whiskey’s jawbone. Nearby were lymph nodes, a ready target and a pathway for the cancer to spread.

    What, then, could be done? The usual course of action was to amputate the affected bone, sometimes using chemotherapy and radiation. Another common treatment involved shaving the growth, Swierk says, but that would also mean subsequent periodic surgeries. With the diseased bone removed, Whiskey’s chances for a full recovery were good. A life without chewing, however, wasn’t so promising.

    After amputation, the jaw is never quite the same. The teeth and bones gradually fall out of alignment, and the dog’s teeth can cause ulcerations in the hard palate. He could eat, but there would be no more chew toys. He could not play ball or tug of war.

    As it turned out, there was another option. A team of vets at the University of California, Davis, had been working on a fix for pets who lost jawbone to disease or injury. It had only been used in five other dogs, but the results had been good. Their vet referred him to the UC Davis School of Veterinary Medicine, 73 miles east of San Francisco.

    It was a done deal for Swierk and Addams, who were prepared to travel to New York, if that’s what it took to not only save their dog, but have him back whole, and to pay the $8,000 treatment cost. Whiskey was more than a pet to them — he was their companion.

    “Whiskey is our world, plain and simple,” Swierk says.

    Bone regeneration was seen as science fiction in 1948, when Dr. Marshall R. Urist, a UCLA orthopedic surgeon who pioneered the field, got started. Urist spent five decades at the bone research laboratory at UCLA, where he discovered how to use proteins to stimulate skeletal repair.

    In 1971, he proposed the name “bone morphogenetic protein” (BMP) for the growth-promoting factors he used to prompt new bone growth in rabbits. The bone proteins act as signals to stem cells, which migrate to them and are converted into bone-forming cells. These cells then grow bone in the area where the BMP was placed.

    Naturally occurring BMP is found within bone, but clinically useful amounts can’t be easily extracted from human donor bone and so must be genetically engineered in the lab.

    At UC Davis, Whiskey was in the care of a team of vets who had been perfecting a new procedure to regrow damaged jawbone, work that drew on Urist’s research and other experimental and clinical treatments developed for humans. The team included Dr. Dan Huey, a biomedical engineer; Dr. Boaz Arzi, a veterinary surgeon; and Dr. Frank Verstraete, who heads the dentistry and oral surgery service at the veterinary teaching hospital. Their goal was to put biomedical approaches to bone replacement to use in veterinary practice. Once they had refined a technique that would work for dogs, they put out the word, and soon referrals from other vets were coming their way.

    “It wasn’t an experimental study, just an innovative application of existing materials,” Verstraete says.

    Over a two-year span, eight dogs have undergone the procedure, and to date, all are doing well, the vets say. Each dog spent three days at the teaching hospital for an exam, surgery and recovery, followed by three post-operative exams.

    Whiskey, their sixth patient, had the largest lesion. There was no getting around it: he would lose much of his jaw. But with the help of a titanium plate, a sponge and some bone proteins donated by Pfizer, he would grow a new one in a matter of months.

    The team’s first task was to decide how much bone to take in order to remove all of the cancer. That proved to be 2.5 inches, or about half of Whiskey’s lower left jawbone. Once the diseased bone was out, in went a titanium plate built by Dr. Arzi, which was screwed into place on the remaining bone.

    But the titanium plate alone was not enough to hold the jaw together. The greatest risk was failure of the plate due to the large gap where the bone had been, Dr. Verstraete says. Over time, pressure on the plate would cause the surrounding bone to resorb.

    Enter the scaffold: a stiff, sponge-like piece of material that was fitted into the space. It, too, was only part of the solution. The next step in building a new jaw would require Whiskey’s own stem cells, attracted to the bone proteins in which the scaffold had been soaked. Like a magnet, the bone proteins would draw stem cells from the dog’s surrounding bone and soft tissue to the scaffold, where they would attach and turn into bone cells, according to Dr. Huey. The new bone cells would eventually fill the entire void and integrate with native bone. On a molecular level, the new bone is the dog’s own, with a DNA makeup identical to other bones in his body.

    There is no need to match the proteins to a particular dog, Verstraete says. “The BMP we use is synthetic, recombinant human (rhBMP-2). It doesn’t elicit any antibody response in experimental animals.”

    Just as the vets borrowed from human medicine, their procedure for dogs will now find its way back into human medicine. Their success with the eight cases has given them material for a report on the work, which they plan to submit to a scientific journal.

    What lies ahead for the promising surgery? The vets hope to be able to modify the technique for use with larger jawbone defects in animals. Also on the horizon: human arm and leg bones. There is more work to be done, however. “The technique that we used has not been done for weight-bearing bones yet,” Verstraete says.

    Is the new method a cancer cure, or a quality-of-life issue?

    “Both,” Verstraete says. “We only do the surgery for tumors that haven’t spread. Reconstruction greatly improves the quality of life compared to the previously used technique.”

    Swierk knows there’s no guarantee that Whiskey will remain cancer-free. “The assumption is that it’s a cure, but the verdict is still out.” But based on Whiskey’s September checkup, it’s “so far, so good.”

    Swierk says the bionic jaw is doing its job. “He eats all his yummies as he did before.” In addition to munching kibble, caulif lower and chew sticks, he’s back to chewing and chasing balls and toys. Swierk isn’t surprised that their dog has bounced back, or that the new technology was available right when he needed it. “We never doubted for one minute that Whiskey would succeed with this new cutting-edge surgery.” It’s all part of Whiskey’s good nature, Swierk says.

    “He’s led a charmed life.”

    Wellness: Health Care
    Compounding pharmacies: a recipe for trouble

    A rare form of human meningitis has already claimed the life 5 people and caused illness in over 40 others. The culprit: an injectable back pain medication made by a Massachusetts compounding pharmacy that was contaminated with a fungal organism.  This news has created an understandable ripple effect that leaves us to question: how does this affect our pets who take compounded medications to manage their disease? 

    As veterinarians, we often recommend the use of compounded medications for several reasons: to convert pills into chicken-flavored chewables or liquids, to create gels that absorb into the skin (for pets who refuse oral medications), to place multiple medications into a single capsule simplifying administration, or to scale down a large dose tablet for a tiny dog.  

    Since compounding pharmacies are not FDA regulated, and offer no guarantee of potency, stability, safety or efficacy, how can we be sure about the quality of the drug being given? This is a vital question when compounded options are needed, and are often the difference between therapeutic success and failure.

    The best way to ensure safety is to have your veterinarian prescribe only through credentialed pharmacies, or those that are in the process of accreditation, by the Pharmacy Compounding Accreditation Board (PCAB). This board was established in 2004 as a voluntary program to ensure adherence to quality and ethical standards. If a pharmacy meets the incredibly rigorous standards set forth by the PCAB, then both veterinarian and owner can be assured that the medications are of the highest quality possible. The board has accredited 50 pharmacies in 40 states thus far, and just as many pharmacies are awaiting accreditation. You can find a list of these accredited pharmacies online here.

    Another word of caution: do not bargain shop when it comes to compounded medications and follow your veterinarian’s recommendations. A recent case of compounding error was reported in a canine patient who was being treated at North Carolina State College of Veterinary Medicine. This dog was being treated with a medicated solution for treatment of Myasthenia Gravis. He was doing excellent on the treatment following discharge, but returned several months later, weak and unable to stand. The owner had taken her written prescription from the vet to a different compounding pharmacy than the one recommended to her. The well-intentioned pharmacist offered to compound the medication into a more “dog-friendly” flavor.  Unfortunately, the pharmacist included methylcellulose in the formulation, which completely bound the active ingredient, making it unavailable for absorption into the body, causing a serious decline in condition. Thankfully, this mistake was realized before the pup was euthanized.  

    Because the compounding industry is growing faster than regulations, it is imperative to be diligent: listen to your veterinarian, do your research, ask questions, and if you are concerned about any safety issues, try to make standard formulations work for your pet.


    Wellness: Health Care
    Hypoallergenic dogs: Fur facts and fictions

    Allergy sufferers who still want to share their home with a canine companion have been known to drop big bucks on breeds that are being touted as “hypoallergenic dogs.” These are dogs who are reported to have lower household allergen levels compared to other pooches. But before you throw out your bottle of Visine and handkerchief, a new study suggests that this just may be fur fiction. 

    Prominent allergen researchers have found that there is no basis to the claim “that certain dog breeds are hypoallergenic” and have found that allergen levels vary among individual dogs, not individual breeds. The American Journal of Rhinology and Allergy published a study in 2011 that revealed the amount of dog allergens found in households does not vary depending on the breed, and families with “hypoallergenic” dogs are living with the same level of allergens in their homes as people who live with a, shall we say, “common” dog.

    The researchers measured the level of the most common dog allergen, Canis familiaris 1, in the homes of 173 families who lived with one dog and found that 163 of them produced measurable levels of Can f 1. The numbers of dogs of each breed were not large enough to allow for analyses by individual breed, but the researchers compared quantities of allergens found in the samples using various categories of purebred and mixed-breed hypoallergenic and non-hypoallergenic dogs. No matter how they did the comparisons- even comparing dogs suggested as being “more hypoallergenic” by the AKC against all other dogs- they found no statistically significant differences in levels of Can f 1.

    The AKC does not actually recommend or endorse any specific breed, nor does it claim that hypoallergenic breeds will not affect people with allergies, but they do suggest 11 canine candidates that have “consistent and predictable coats” that may benefit allergy sufferers. Basically, these are the breeds that have more of a non-shedding coat, which in turn produces less dander, and therefore less allergens in the environment.

    How then, was the legend of the hypoallergenic dog born? Good question, as no one really knows where the whole concept got its start. But perform an internet search with the terms “hypoallergenic dog” and you will see endless links touting the perfect allergy-free pooch. I was most shocked when I read about Simon Brodie of Lifestyle Pets, a controversial U.S.-based company that breeds and sells cats and dogs as “hypoallergenic” at a price of $16,000 each! And, no, that was not a typo with an extra one or two “0’s” on the end!

    So, if there are no “real” hypoallergenic dogs, what can you do to reduce the sniffling and sneezing? Here are some tips:

    • Make sure your pet’s essential fatty acid requirements are met. By assuring your dog or kitty has optimal levels of EFAs in the diet, you can reduce shedding and dander associated with EFA deficiency. Adding coconut oil has also proven to help reduce dander and shedding.

    • Bathe your pet often. Even kitties can be bathed regularly, but take special care to use only safe, non-drying herbal animal shampoos. Whatever you do, avoid using people shampoo on your dog or cat, and skip any shampoo containing oatmeal.

    • Invest in a good-quality vacuum designed for households with pets.

    • Clean your home frequently and thoroughly, including any surfaces that trap pet hair and dander like couch covers, pillows and pet beds. This will also help control other allergens in your home that could be contributing to the allergic load of family members.

    • Wash bedding frequently in hot water.

    • If your pet rides in the car with you, consider using washable seat covers.

    • Purchase a good quality air purifier for your home.

    • If possible, remove carpeting, drapes and other fabric that traps animal dander. Tile or wood floors are much easier to clean of allergens.

    By following these tips, you may be able to lessen the allergenic load in your environment and live more harmoniously with your canine companions.


    Wellness: Health Care
    DIY Physical Exam: An “owner’s manual” for your dog Part 4
    Part 4 in 4 part guide
    Doing DIY Physical Exams on Dogs

    Welcome back for the last installment of the DIY physical exam for your dog! We have reached “the tail end” of things so to speak, and will be finishing up our discussion with learning some “belly basics” as well as what to watch out for with the musculoskeletal system.


    The exam is pretty straightforward: touch and feel the stomach, starting just behind the ribs and gently press your hands into the belly. Like all other parts of the body, you will be getting a feel for what is normal, and then continuing to monitor for any future changes. If your pet has just eaten, you may be able to feel an enlargement in the left part of the belly just under the ribs (where the stomach “lives”), which can be normal just after eating. Continue by proceeding toward the rear of the body, passing your hands gently over the entire area.


    • No lumps, bumps, or masses
    • No discomfort on palpation
    • No distention of the belly


    • Any lump, bump, or mass may be abnormal
    • Palpation that causes groaning or difficulty breathing: any evidence or indication of pain is a serious finding and requires immediate attention; sudden and marked belly pain is what we refer to as “an acute abdomen” and can be caused by various conditions including pancreatitis (inflammation of the pancreas), sepsis (an infection in the belly that can be caused by a ruptured bowel or foreign body such as a foxtail), bleeding into the belly (such as from rat bait or a ruptured spleen), trauma, tumors or abscesses
    • If the abdomen feels hard or tense and it appears distended: this is one of the major signs of bloat or GDV and immediate attention is needed! 


    There are many conditions that can all look like “a basic lameness” in our pets. Below are a few of the more common presentations I see and their potential causes.


    • Lameness in any single leg: when a pet becomes lame, sources of the discomfort can be from the bone, soft tissue, joints, or tendon/ligaments.
    • A persistent, non-resolving lameness despite rest and medications: another thing that needs to be considered is a type of bone cancer called Osteosarcoma; this can be common finding in the long bones of large breed, older dogs and an X-ray can be performed to screen for this type of cancer; another typical presentation for bone cancer that I see is a pet that develops a very sudden and severely painful lameness following a “simple” act, such as jumping off the porch.
    • Swelling of the joints: common causes include infectious diseases (tick-borne disease, septic joints), immune mediated disease, vaccine-related reactions, and degenerative joint diseases.
    • Loss of function or paralysis in hind legs: some causes include disease processes such as a herniated disk, cancer, infection, narrowing between the vertebrae of the spine, or degenerative myelopathy; losing the ability to walk is an emergency and immediate care is needed to help improve your pet’s chances of regaining mobility!
    • Recurring, shifting leg lameness, pain, and fever in a young dog: Panosteitis is a disease of the long bones of mostly young, growing large breed dogs; German Shepherd males are most frequently affected but any large breed dog can be affected.
    • Limp tail: this is also known as “limber tail” or “cold tail” and is a condition in which a working dog suddenly develop a flaccid tail; affected dogs usually have a history of prolonged cage transport, a hard workout the previous day, swimming, or exposure to cold or wet weather; most dogs recover spontaneously within a few days to weeks but evaluation by your veterinarian should be done because there are other diseases that can mimic a “limber tail” such as a tail fracture, spinal cord disease, impacted anal glands, and prostatic disease.

    I hope this systems approach to an “at-home physical exam” helps you to become familiar and stay in tune with what is normal for your pet. Performing this exam in the comfort of your own home is the best way to learn what is normal and helps you to recognize any early changes in your pets behavior. Consult your veterinarian if an abnormal condition exists or you are concerned about any exam finding.  Early recognition can save the life of your pet! 

    By no means is this list exhaustive, and this information is intended as a general reference; it is not intended to replace professional advice or an examination by a veterinarian. 


    Wellness: Healthy Living
    Vet Advice: Relief for Your Dog's Itchy Skin
    Addressing the second most common problem on the vet hit parade

    Question: Recently, my dog's nighttime scratching is keeping both of us awake. Her fur seems dry and a bit dandruffy, and she also seems to be shedding more than usual. What can I do to help her?

    Answer: Dogs itch for many different reasons, and sometimes, for no reason, and it’s not uncommon for the scratching to seem worse at night, when the house is quiet. Every dog’s gotta scratch some time, and that’s completely normal. But when a dog is incessantly licking, scratching, biting and chewing to the point of wounding herself, then scratching becomes a symptom of an underlying pathology.

    The medical term for scratching related to excessive itching is pruritus. This is the second most common reason people take their dogs to the vet (gastrointestinal problems such as diarrhea top the list). The causes of pruritus can be quite complex, but there are two main reasons why dogs itch. The first has to do with the condition of the skin itself: Is it infected? Is it too oily? Is it too dry? Of these three, dry skin is a frequent occurrence. The second major cause of pruritus is allergies.


    Is It Dry Skin?
    One common cause of itching is dry skin. If you live in a region with low humidity, it’s more likely that your dog will have dry skin, which is fairly easy to recognize. When you part your dog’s hair, you see flakes of dandruff in the undercoat, and the skin itself may be cracked and tough. The slightest stimulation of the skin—your gentlest touch—can provoke your dog to scratch violently.

    Dry skin can be influenced not only by environmental factors, but also by diet. Commercial pet foods process out the good oils that contribute to healthy skin and a lustrous haircoat. Dry pet foods have an even more dehydrating effect on skin and hair and also stimulate increased thirst, which only partially compensates for the drying nature of these diets.

    If you must feed dry foods, then by all means add digestive enzymes to your dog’s meals. In fact, digestive enzymes are good to use with any type of food. Enzymes improve the release of nutrients, and beneficial probiotic bacteria also assist in the digestive process. (Probiotics also help with allergies, as noted below.) A healthy digestive system absorbs fluids more readily from the food your dog eats, thus improving hydration and increasing the moisture levels of the skin and haircoat.


    Or Allergies?
    Another common cause of itchy skin is allergies. Allergies may make your dog’s skin dry, greasy, or slightly dry and oily, and are accompanied by frequent scratching, licking or chewing. We are seeing significantly more cases of allergic dogs than we have in the past; many veterinarians believe that we are experiencing an “allergy epidemic.” While the reasons for this allergy epidemic are uncertain, some of the theories put forth include the aggressive vaccination protocols that many dogs have been subjected to, poor breeding practices and the feeding of processed pet foods.

    Whatever the cause, allergies are difficult to address. In the worst cases, afflicted dogs require strong (and potentially toxic) pharmaceuticals just to get some relief. Though allergies are rarely cured, early identification and intervention can keep them under control, and in some cases, can substantially diminish them.

    Clinical research has shown that one important way to reduce the likelihood that dogs will develop allergies is to give them high-potency cultures of beneficial probiotic bacteria such as Lactobacillus acidophilus and Lactobacillus bifidus when they are very young. Probiotics are relatively inexpensive, absolutely safe to use, and can save both dog and the owner tons of grief—and visits to the vet—later in life.

    Regardless of age, many dogs’ allergies are controlled by improving the quality of their diet, giving them high potency acidophilus cultures and high doses of fish oils; adding freshly milled flax seed; and, in some cases, giving them antihistamines. (It can take up to three months for this regimen to take effect; see sidebar for details and dosages.)

    Determining which condition your dog is dealing with requires a vet’s evaluation, but implementing some of the suggestions provided in the sidebar can certainly help your pup be more comfortable in her own skin—literally.

    Wellness: Health Care
    Second Opinion: Magic Act
    A Vet’s Perspective
    Magic Act: Second Opinion

    Every day in veterinary emergency rooms across the country, shocked, distraught and overwhelmed dog owners face tough decisions. In addition to medical complexities and ambiguities, they deal with guilt, fear, grief and, sadly, money. But for Kathy Noons and her seven-year-old Boston Terrier, Tessie, it was all about hope.

    Although Ms. Noons had asked her dog-walker to keep Tessie leashed, the woman often let her run loose with other dogs, and Tessie clearly loved it. But then came the phone call: The dogwalker had lost Tessie. It was January. The little dog was found the next morning, miles away, lying in a cemetery.

    When Tessie arrived at the Angell Animal Medical Center ER, she had a temperature of 86.7°F (normal is around 101°F), the bones of her pelvis were shattered and, as a result of spinal trauma, she was paralyzed and incontinent.

    Barely responsive, Tessie was so cold that warming her up had to be done slowly over the course of several hours to avoid further shocking her system. Blood and urine were drawn and tested, she was X-rayed and an ultrasound was performed. Throughout it all, she received intravenous fluids and medications for pain.

    Eventually, Ms. Noons was presented with a long list of negatives that, when added up, suggested that euthanasia would be the kindest course of action. As she retold it, “That’s when I said, ‘C’mon, throw me a bone (no pun intended),’ [and] one doctor told me what I needed to hear. She said there’s always a chance.”

    It took a few days for Tessie to stabilize, and that’s when I got involved. Ms. Noons later told me her biggest fear was that I would refuse to operate … that I would tell her it was futile. To be honest, it crossed my mind. Despite surgery, the risk of permanent nerve damage, incontinence and an inability to stand, let alone walk, was significant. But sometimes, if you put everything back in place, screw it all together and take a leap of faith, tissue heals. Tessie’s injuries were really bad, but not hopeless.

    Though the odds were slim at best, I believed surgery offered her at least the possibility of a cure. An uncertain prognosis can be like a bad trip to Vegas, a gamble in which the only way out is through — risky, all or nothing. But that’s the hand we were dealt, and it was the one we played.

    My involvement in Tessie’s recovery, while important, was brief and, to be honest, secondary. I reconstructed her broken pelvis with plates and screws, but the critical-care doctors and attentive technicians gave her the chance Ms. Noons sought. Yes, it takes a team to heal a “humpty-dumpty” dog, but in the jigsaw puzzle of putting Tessie back together, I only did one or two of the corners. Tessie’s primary-care team did all the tricky, thankless stuff.

    Once Tessie was released from the hospital, Ms. Noons was committed to giving her the best possible chance to recover. Diapers, pain meds, hydrotherapy, acupuncture: Whatever Tessie needed, Ms. Noons provided. Ultimately, this level of commitment, this steadfast conviction, paid off. Three months after surgery, Tessie was running around, chasing other dogs and fully continent. Why this dog made it and a dozen others with the exact same injuries would not, I can’t say. Maybe a dog who can survive being hit by a car and a cold January night in Boston has an extra helping of luck.

    “She was always a source of pride,” says Ms. Noons. “People would stop me and want to play with her. When they saw her in a diaper, barely able to walk, I could tell they were thinking, Is it fair what you’ve done to your dog?”

    “How’s it feel today,” I say, “when you meet these naysayers in the street?” “It’s nice to be smug; I’m not going to say it isn’t. I’m proud of her, being fresh, going after bigger dogs. My princess is back.”

    Ms. Noons marvels at what we did for Tessie and, though I appreciate (and am humbled by) her gratitude, it’s far more than I deserve. Perhaps the hands-on nature of surgery, the physicality of mending broken bones, the instant gratification of postoperative X-rays, makes it look as though the doctor with the scalpel created the cure. Truth is, I’m as amazed as she is, and under no illusion; in this magic act, I was nothing more than a willing assistant.

    Wellness: Health Care
    DIY Physical Exam: An “owner’s manual” for your dog Part 3
    Part 3 in 4 part guide
    Animal, Dog DIY At-Home Dog Physical Examinations

    Welcome back for part three in our four-part DIY physical exam! This week we are going to move down to the chest area, known as the thorax. 



    • You should not be able to hear your pet breathe at all (except with panting).
    • The act of breathing is for the most part performed by the chest wall; it should move “in and out” easily and rhythmically to and fro during respiration in an effortless way; each breath should look the same as the last.
    • The normal resting respiration rate is 15 to 60 breaths per minute; a sleeping or relaxed dog would be near the low end, while an active and engaged dog would be higher; and just like with heart rates, smaller dogs will tend to have a faster resting breathing rate than our larger dogs.


    • Any unusual noise heard while the dog is breathing could indicate a problem, especially if the noise is new for your pet.
    • A big concern: a change in your dog’s bark can indicate disease processes such as laryngeal paralysis (a common condition in our older large breed dogs such as Labs) or the development of a tumor in the airway.
    • Wheezing during expiration can indicate conditions such as asthma or allergic airway disease .
    • High pitched noises on inspiration indicate an obstruction of the upper airway and immediate medical attention is needed (see our previous blog).
    • Sudden or frequent sneezing can indicate foreign objects in the nasal passages, such as foxtails.
    • If there is noticeable effort by your dog to move the chest wall, or if the belly is actively involved in the process of inhaling and exhaling: these are signs of respiratory distress and can be caused by many conditions.
    • The onset of coughing in an older dog: coughing is one of the more common signs of the development of heart failure or lung cancer in dogs; x-rays of the chest will be needed to further evaluate if you notice this symptom.
    • Your dog stands with elbows held out further than normal, its neck extended out further than normal or, is unable to rest or lie down: these are all outward signs that your dog is having difficulty breathing and getting enough oxygen into its body.
    • An increased resting respiratory rate can be a sign that a previously diagnosed disease is progressing; for example: if your dog with heart disease has a normal resting rate of 15 breaths a minute, and then the resting rate goes up to 30 while asleep, then doubled rate means it’s time to see the veterinarian.


    The skin is one of the body’s major organs and it is an important indicator of overall health. The first things to do are to simply look at, smell, and feel your dog’s skin and haircoat.


    • Shiny and smooth haircoat (except for wirehaired breeds)
    • Soft and unbroken skin
    • Minimal odor


    • Sparse or patchy haircoat: this can indicate underlying endocrine diseases such as Cushing’s disease.
    • Lumps and bumps, which can be normal or abnormal: many older dogs can develop accumulations of fatty tissue known as lipomas; in order to differentiate these benign masses from cancerous ones, an aspirate can be performed (collection of cells with a small needle); this simple and quick procedure can help your veterinarian determine the nature of the lump and help you decide if further tests or treatment are needed.
    • Open sores or wounds, or any ulcerated area of skin.
    • Foul or rancid odor: this can indicate a bacterial or yeast infection in the skin.


    The skin turgor test is one of the most helpful ways to determine whether your pet is well hydrated; although this test can be affected by several factors other than hydration status, such as weight loss, age and general skin condition, it can help you to make a rough determination of the hydration status. To perform this test, pull up the skin over the neck or back into “a tent” and release it quickly: it should return quickly to its resting position. If the skin returns slowly to position, or if remains slightly tented, then this is a good indication that your pet is dehydrated.

    That sums up the thorax region of our pets, including one of the other major organs—the skin.  Keep practicing your physical exam skills—it’s definitely a win/win for your dog! Not only does your pet get a good “once over” from you, he or she gets even more hands-on attention in the process. See you next week as we move to the last parts of the body which will include the abdomen and musculoskeletal system.

    Check out DIY Physical Exam: Part 2 of this series if you missed it. Go on the next final part, DIY Physical Exam: Part 4.