Home
Guest Posts
Print|Email|Text Size: ||
Mysteries of the Basset Hound Revealed
Scientists isolate the gene behind short legs.
The genetic mutation that keeps some dogs from developing long legs may go back more than 300 years.

A new study published in Science identifies the single evolutionary event that shortened the legs of Dachshunds, Basset Hounds and other stubby puppies. An extra copy of a gene (Fgf4 retrogene, to be exact), acquired by mutation at least 300 years ago, “causes the overproduction of a protein that disrupts growth during fetal development,” writes Sarah Arnquist, translating the study for a New York Times science blog.

I’m freaked out by efforts to engineer animals to suit our needs—according to Arnquist’s story, one advantage of shorter legs in Basset Hounds was allowing hunting humans on horseback to keep up. Plus, it’s hard to ignore the costs of tinkering. Last year’s BBC documentary, “Pedigree Dogs Exposed,” revealed just a few of the devastating health consequences of breeding for exaggerated physical characteristics.

But, all that said, these results have significant implications. First, it’s more evidence that all the investment of time and money in creating a dog genome is paying off. Secondly, discovering the gene behind Chondrodysplasia in dogs probably holds important clues into dwarfism in humans. I think it’s fascinating that dogs, so helpful to us in our everyday life as companions and assistants, are providing important keys to unlocking human health mysteries. 

Print|Email
Lisa Wogan lives in Seattle and is the author of, most recently, Dog Park Wisdom. lisawogan.com

iStockphoto.

CommentsPost a Comment
Please note comments are moderated. After being approved your comment will appear below.

More From The Bark

By
Lisa Wogan
By
Lisa Wogan
By
Lisa Wogan
More in Guest Posts:
Zoey and Jasper
Zoo Baby: Part 3
Pet Loss Research:
App Review: Dog Decoder
Home-Schooling for Dogs Could Be Catching On
Wisdom Has Gone to the Dogs
Pub Dogs
Zoo Baby: Part 2
Rufo's Story
Canine Urination 101: Handstands and Leg Lifts Are Just the Basics